Gut bacteria transplant could tame Crohn's inflammation
NCT ID NCT06631586
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether capsules containing freeze-dried healthy donor gut bacteria can take root in the intestines of people with Crohn's disease. Researchers will check if the bacteria engraft in the ileum and colon, and explore changes in symptoms and inflammation. The trial involves 120 adults with active Crohn's disease who are already on stable treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fecal microbiota transplant (FMT) capsules
What this could lead to
If successful, this could point toward a new way to treat Crohn's disease by restoring healthy gut bacteria, potentially reducing inflammation and symptoms.
What could go wrong
This is an early phase 2 trial with only 120 participants, so results may not apply to everyone. The treatment may not engraft effectively or improve symptoms, and side effects like bloating or infection are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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NYU Langone Health
NOT_YET_RECRUITINGNew York, New York, 10016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
Contact Email: •••••@•••••