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Can a special MRI match CT for spotting knee bone damage?

NCT ID NCT07827443

Diagnosis Sponsor: Assiut University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Researchers at Assiut University are testing whether a specialized MRI technique called multi-echo fast field echo (mFFE) can detect cortical bone changes in knee osteoarthritis as accurately as CT scans. The study enrolls 80 adults aged 40 and older with suspected or confirmed knee osteoarthritis. Participants undergo both mFFE MRI and CT, and researchers compare how well the MRI identifies bone damage against CT, which serves as the reference standard. The goal is to see if mFFE MRI could offer a radiation-free alternative for evaluating bone changes in knee osteoarthritis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
multi-echo fast field echo (mFFE) MRI
What this could lead to
If mFFE MRI matches CT for spotting cortical bone damage, people with knee osteoarthritis could get detailed bone imaging without CT radiation.
What could go wrong
This is a single-center imaging study of 80 people, so results may not hold in other scanners, hospitals, or patient groups. MRI also cannot be used by people with certain implants or metal fragments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Feb 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 40 years or older with clinically suspected or confirmed knee osteoarthritis attending the Diagnostic and Interventional Radiology Department at Assiut University Hospital.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- Age 40 years or older * Clinically suspected or confirmed knee osteoarthritis * Able and willing to provide informed consent Exclusion Criteria: * \- Implanted electronic devices (pacemakers, ICDs, neurostimulators, cochlear implants) * Metallic foreign bodies in the eyes or orbits * Ferromagnetic cerebral aneurysm clips * Implantable infusion pumps * Pregnancy

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Conditions

The condition(s) this trial relates to.

bone disorder osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone diseases Osteoarthritis, knee

How to take part

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  1. The official record

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