New study tests methadone to curb opioid dependence after spine surgery
NCT ID NCT07222072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving methadone during and after major spine surgery can reduce the need for other opioids three months later. About 120 adults having multi-level spine fusion will be randomly assigned to receive methadone or a placebo. The goal is to see if this approach is safe and practical, and to gather data for a larger future trial.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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