Diabetes drug shows promise against rectal cancer in new trial
NCT ID NCT02437656
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding metformin, a common diabetes medicine, to standard chemo and radiation therapy could help people with locally advanced rectal cancer. 60 adults with stage T3 or T4 rectal cancer took part. The main goal was to see if the combination led to a complete disappearance of cancer cells in the tumor after surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre Galilée - Hôpital Privé La Louvière
Lille, 59045, France
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Centre Gray
Maubeuge, 59600, France
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Centre Hospitalier
Lens, 62300, France
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Centre Joliot-Curie
Saint-Martin-Boulogne, 62200, France
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Centre Léonard de Vinci - SARL du pont Saint Vaast
Douai, 59500, France
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Centre Marie Curie
Arras, 62000, France
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Centre Oscar Lambret
Lille, 59020, France
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Centre Pierre Curie
Beuvry, 62880, France
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Clinique des Dentellières
Valenciennes, 59300, France
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Clinique du Bois - Centre Bourgogne
Lille, 59000, France
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Institut André Dutreix
Dunkirk, 59240, France