Menthol E-Cigs under the microscope: do they boost nicotine and risk?

NCT ID NCT05338801

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how menthol flavor in e-cigarettes affects users' puffing habits, nicotine levels, and dependence compared to tobacco flavor. Researchers will have 250 young adults (ages 21-35) use both flavors in separate lab visits. The goal is to provide evidence for the FDA to decide if menthol-flavored e-cigarettes should be regulated to reduce harm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Menthol-flavored e-cigarette liquid
What this could lead to
If successful, this study could help the FDA decide whether to regulate menthol-flavored e-cigarettes to reduce harm among young users.
What could go wrong
This is an early-stage observational lab study, not a treatment trial. Results may not reflect real-world use or apply to all e-cigarette users.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Vaping

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Florida International University

    RECRUITING

    Miami, Florida, 33199, United States

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