Brain test may predict Alzheimer's drug response
NCT ID NCT03703856
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether simple brain function measures can predict which Alzheimer's patients will respond to the drug memantine. 53 participants with mild-to-moderate Alzheimer's took memantine or placebo, then all received memantine for 24 weeks. The goal was to see if early brain responses could guide personalized treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Memantine
What this could lead to
If successful, this could help doctors predict which Alzheimer's patients will benefit most from memantine, leading to more personalized treatment.
What could go wrong
This is a small, completed Phase 4 study with only 53 participants, so results may not apply to all Alzheimer's patients. The benefit of memantine is modest and not guaranteed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Teaching Facility (CTF-B102) at UCSD Medical Center
San Diego, California, 92103, United States