New combo therapy shows promise against advanced melanoma before surgery

NCT ID NCT04526730

First seen Nov 19, 2025 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tested a new approach for people with advanced melanoma that can be surgically removed. Participants received a combination of two immunotherapies: one injected directly into the tumor (Tavo) and one given through a vein (nivolumab) before surgery. The goal was to see if this treatment could completely eliminate the cancer before the operation. The study involved 17 adults and has been completed.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

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