Could your genes raise your melanoma risk? new study seeks answers

NCT ID NCT00040352

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 31 times

Summary

This study aims to understand why some people and families are at high risk for melanoma, a serious skin cancer. Researchers will collect medical history, blood or cheek cell samples, and skin biopsies from 3,000 participants with a personal or family history of melanoma. The goal is to identify genetic and environmental factors that contribute to melanoma and related conditions, which could improve future prevention and early detection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Cancer Institute (NCI)

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could identify genes and risk factors that help predict who is most likely to develop melanoma, leading to better screening and prevention strategies.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly benefit participants. Results may take years and might not apply to everyone with melanoma risk.

Conditions

The condition(s) this trial relates to.

melanoma melanoma, cutaneous malignant, susceptibility to, 2 skin neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.