Can a blood test predict who will respond to melanoma immunotherapy?

NCT ID NCT05105100

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined blood and tumor samples from 25 people with advanced melanoma who were starting standard pembrolizumab treatment. Researchers looked at T cells—key immune cells—to find patterns that might predict whether the therapy works. The goal is to better understand why some patients respond and others don't, without testing any new drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which melanoma patients will benefit from immunotherapy, leading to more personalized treatment.
What could go wrong
This is a small, observational study with only 25 participants, so results may not apply to everyone. It does not test a new treatment, only looks at existing data.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

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