New ointment may soothe radiation mouth pain better than standard rinse

NCT ID NCT07186114

Completed Symptom relief Sponsor: Cairo University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested two treatments for painful mouth sores caused by radiation therapy: MEBO ointment and Tantum Verde mouthwash. 36 adults with moderate to severe sores were randomly assigned to one treatment for two weeks. Researchers measured soreness and healing at the start, after one week, and after two weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MEBO ointment and Tantum Verde mouthwash
What this could lead to: If MEBO works better, it could offer a new option to ease painful mouth sores from radiation therapy.
What could go wrong: This is a small, single-center trial with only 36 patients, so results may not apply broadly. Both treatments are already available, so no major breakthrough is expected.

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Conditions

The condition(s) this trial relates to.

stomatitis ulcer disease ulcerative stomatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ORAL MUCOSITIS (ULCERATIVE) DUE TO RADIATION

Contacts and locations

Locations

Cairo University

Cairo, Egypt
Faculty of Dentistry - Cairo University

Cairo, 11553, Egypt

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