Can a stem cell spray stop radiation mouth pain?

NCT ID NCT07312656

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an oral spray made from stem cell exosomes to prevent severe mouth sores in head and neck cancer patients undergoing radiation. 200 participants will use the spray three times daily, starting a week before radiation and continuing for two weeks after. The goal is to see if it reduces the number of patients who develop painful, high-grade mouth ulcers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mesenchymal stem cell-derived exosomes

What this could lead to

If it works, this could provide a new way to prevent painful mouth sores caused by radiation therapy, improving quality of life for head and neck cancer patients.

What could go wrong

This is a Phase 2 trial, so it is still early. The treatment may not reduce severe mouth sores more than standard care, and side effects from the exosome spray are not yet fully known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer stomatitis ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Guangxi Medical University

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••