Could mangosteen help control type 2 diabetes?

NCT ID NCT07172269

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether adding a mangosteen supplement to standard diabetes drugs (sitagliptin/metformin) improves blood sugar control in 47 adults with type 2 diabetes. Participants took either the standard drugs alone or with mangosteen for 12 weeks. Researchers measured changes in HbA1c, insulin resistance, and inflammation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mangosteen supplement (Garcinia mangostana extract)
What this could lead to
If it works, this could point toward a natural supplement to help manage blood sugar and reduce inflammation in type 2 diabetes.
What could go wrong
This is a small, early-stage trial with only 47 patients. Results may not apply to everyone, and supplements are not a replacement for standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Inflammation Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Diabetes Center for Treatment and Research

    Baghdad, Iraq

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