Could mangosteen help control type 2 diabetes?

NCT ID NCT07172269

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether adding a mangosteen supplement to standard diabetes drugs (sitagliptin/metformin) improves blood sugar control in 47 adults with type 2 diabetes. Participants took either the standard drugs alone or with mangosteen for 12 weeks. Researchers measured changes in HbA1c, insulin resistance, and inflammation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mangosteen supplement (Garcinia mangostana extract)

What this could lead to

If it works, this could point toward a natural supplement to help manage blood sugar and reduce inflammation in type 2 diabetes.

What could go wrong

This is a small, early-stage trial with only 47 patients. Results may not apply to everyone, and supplements are not a replacement for standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Inflammation Insulin Resistance type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Diabetes Center for Treatment and Research

    Baghdad, Iraq