Scientists probe lymph nodes to unlock cat allergy mysteries

NCT ID NCT07447869

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at immune cells in the lymph nodes of 16 cat-allergic adults. Half are on long-term allergy shots (immunotherapy), half are not. Researchers will give a small cat allergen injection and then sample lymph nodes and blood to see how many analyzable cells they can collect. The goal is to better understand the immune response, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
intradermal cat allergen challenge
What this could lead to
If successful, this study could improve understanding of how cat allergy immunotherapy works at the cellular level, potentially guiding better treatments.
What could go wrong
This is a very small, early-phase study (16 participants) focused on feasibility and cell collection, not on treatment outcomes. It may not lead to any direct benefit for participants or change clinical practice.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital: Division of Allergy and Clinical Immunology

    RECRUITING

    Boston, Massachusetts, 02215, United States

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