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Simple booklet may boost genetic testing in lynch syndrome families

NCT ID NCT07106359

Recruiting now Knowledge-focused Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 22, 2026 · Updated 3 times

Summary

This study tests whether providing an information letter plus a booklet helps relatives of people with Lynch syndrome decide about genetic counseling and testing. About 185 untested relatives will be randomly assigned to receive either a basic letter or a letter plus a detailed booklet. Researchers will track how many people use the materials, schedule genetic services, and complete follow-up surveys over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
educational materials (information letter and booklet)
What this could lead to
If successful, this could show that simple educational materials help more at-risk relatives get genetic counseling and testing, potentially preventing cancers.
What could go wrong
This is a small pilot study testing feasibility, not effectiveness. Results may not apply to all populations, and the materials may not change behavior significantly.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Colorectal Neoplasms, Hereditary Nonpolyposis Lynch syndrome uterine cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER PREVENTION CASCADE TESTING COLORECTAL CANCER DECISION MAKING LYNCH SYNDROME UTERINE CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UAB

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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