New drug aims to shield kidneys during heart surgery

NCT ID NCT05879432

First seen Jan 10, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study tests an investigational drug called LSALT peptide to see if it can prevent or reduce acute kidney injury (AKI) in people having heart surgery with a heart-lung machine. About 240 adults will be randomly assigned to receive either the drug or a placebo. The main goal is to see if fewer people in the drug group develop kidney problems within a week after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cumming School of Medicine & Libin Cardiovascular Centre, University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 4N1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erciyes University, Faculty of Medicine - Semiha Kibar Organ Transplant & Dialysis Hospital

    RECRUITING

    Melikgazi, Kayseri, 38030, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gazi University

    RECRUITING

    Yenimahalle, Ankara, 06560, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kocaeli University, Faculty of Medicine Practices and Research Hospital

    RECRUITING

    İzmit, Kocaeli, 41001, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kosuyolu High Specialization Training and Research Hospital

    RECRUITING

    Kartal, Istanbul, 34865, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Columbian Hospital

    NOT_YET_RECRUITING

    New Westminster, British Columbia, V3L 0A2, Canada

    Contact Phone: •••-•••-••••

  • Sütçü İmam University, Faculty of Medicine

    RECRUITING

    Kahramanmaraş, Onikişubat, 46040, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Unity Health Toronto, St. Michael's Hospital

    RECRUITING

    Toronto, Ontario, M5B 1W8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Health Network, Toronto General Hospital

    RECRUITING

    Toronto, Ontario, M5G 1L7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.