MRI-Guided radiation aims to cut bowel side effects in prostate cancer

NCT ID NCT06171269

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using MRI scans to guide radiation can lower the dose to healthy parts of the prostate while targeting cancer spots. The goal is to reduce bowel-related side effects without losing cancer control. About 60 men with intermediate- or high-risk prostate cancer will receive daily radiation for 4 weeks, plus hormone therapy for 6–24 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy

What this could lead to

If successful, this approach could reduce bowel side effects from radiation while still controlling prostate cancer, improving quality of life.

What could go wrong

This is a small, early-phase study with only 60 participants, so results may not apply to everyone. The lower radiation dose might also be less effective at controlling cancer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate adenocarcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Medicine Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact