Botox injection study aims to heal painful anal fissures
NCT ID NCT07543315
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 3 trial tested two doses of Botox (20 vs 50 units) injected into the anal sphincter to treat chronic anal fissures in 70 adults. The goal was to see which dose better heals the fissure, reduces pain, and allows a quicker return to daily activities. Researchers followed participants for one year to check healing and side effects like incontinence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Botulinum toxin type A (Botox)
- What this could lead to
- If successful, this could help doctors choose the best dose of Botox to heal chronic anal fissures and reduce pain with fewer side effects.
- What could go wrong
- This is a small, completed trial with only 70 participants, so results may not apply to everyone. Botox injections can cause temporary incontinence or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Medicine Tanta University
Tanta, Egypt
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