Back pain puzzle: scientists probe whether body changes are here to stay or come and go

NCT ID NCT06412484

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study investigates whether certain physical and brain changes in people with episodic low back pain are always present (trait-like) or only appear during a pain episode (state-like). Researchers will compare results from pain-free days and painful days using sensory tests, brain scans, and blood samples. The goal is to better understand the nature of low back pain, which could eventually lead to more targeted treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help distinguish lasting changes from temporary ones in low back pain, guiding more personalized treatments.
What could go wrong
This is an observational study with no treatment being tested. It may not lead to direct clinical benefits or apply to all types of back pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Low Back Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Balgrist Campus

    Zurich, 8008, Switzerland

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Other studies related to the condition(s) this trial covers.