Cooking method matters: simple diet change shows promise for diabetes and heart health

NCT ID NCT07303842

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested a low-AGE diet in 36 adults aged 55-65 with type 2 diabetes, coronary artery disease, and overweight. Participants were instructed to boil or steam food instead of frying, grilling, or roasting. The diet reduced blood levels of a harmful compound called CML by 30%, which may help with insulin resistance and blood vessel health. While promising, the study was small and short-term, so more research is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-advanced glycation end products (AGE) diet (boiling/steaming food, avoiding frying/grilling/roasting)

What this could lead to

If confirmed, this diet approach could help manage type 2 diabetes and reduce heart disease risk by lowering harmful compounds in the blood.

What could go wrong

This was a small, short-term study with only 36 participants. Long-term benefits and broader applicability are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CORONARY ARTERY DISEASE (CAD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

coronary artery disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Servico de Prevencao, Cardiopatia na Mulher e Reabilitacao Cardiovascular, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP,

    São Paulo, São Paulo, 05403- 900, Brazil