Blood pressure pill may stop knee scarring after ACL surgery

NCT ID NCT07135687

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether losartan, a common blood pressure medicine that also reduces scarring, can prevent abnormal scar tissue (arthrofibrosis) in the knee after ACL reconstruction. About 144 adults having ACL surgery will take losartan or a placebo. The main goal is to see if it helps maintain knee range of motion over 12 months.

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

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