New cocktail aims to make pancreatic tumors removable

NCT ID NCT03563248

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests whether adding losartan (a blood pressure drug) and nivolumab (an immunotherapy) to standard chemotherapy and radiation can help shrink pancreatic tumors enough for successful surgery. About 168 people with localized pancreatic cancer that is borderline or locally advanced will participate. The main goal is to see if more patients can have their tumors completely removed with clear margins.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Newton Wellesley Hospital

    Newton, Massachusetts, 02462, United States

  • Sibley Memorial Hospital

    Washington D.C., District of Columbia, 20016, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • University of Colorado Cancer Center

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.