Promising cocktail targets tough pancreatic tumors

NCT ID NCT03563248

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding losartan (a blood pressure drug) and nivolumab (an immunotherapy) to standard chemotherapy and radiation can improve surgery outcomes for people with localized pancreatic cancer. About 168 participants with borderline resectable or locally advanced tumors will receive the combination. The main goal is to see if more tumors can be completely removed with clear margins.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • New York University Langone Medical Center

    New York, New York, 10016, United States

  • Newton Wellesley Hospital

    Newton, Massachusetts, 02462, United States

  • Sibley Memorial Hospital

    Washington D.C., District of Columbia, 20016, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • University of Colorado Cancer Center

    Aurora, Colorado, 80045, United States