New triple therapy aims to deepen remission in untreated CLL
NCT ID NCT07218510
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a newer drug, epcoritamab, to a standard two-drug combination can improve outcomes for people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The standard combo (venetoclax + obinutuzumab) is already effective, but the hope is that epcoritamab will help the immune system kill more cancer cells, leading to deeper and longer remissions. About 33 adults who have not received prior treatment for CLL/SLL will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Atlanta Cancer Center
RECRUITINGNewnan, Georgia, 30265, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at Irvine Lennar
RECRUITINGIrvine, California, 92618, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at Long Beach Elm
RECRUITINGLong Beach, California, 90813, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
NOT_YET_RECRUITINGNew York, New York, 10016, United States
Contact Email: •••••@•••••
Contact
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Medical College of Wisconsin
NOT_YET_RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact Email: •••••@•••••
Contact
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University of Miami Miller School of Medicine-Sylvester Cancer Center
NOT_YET_RECRUITINGMiami, Florida, 33136, United States
Contact Email: •••••@•••••
Contact