Triple-Drug attack aims to wipe out leukemia cells for good

NCT ID NCT07218510

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 30 times

Summary

This study tests whether adding a newer drug, epcoritamab, to a standard two-drug combination can make cancer disappear more completely and for longer in people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). About 33 adults who have not had prior treatment will receive venetoclax and obinutuzumab first, then epcoritamab. The goal is to see if this triple therapy leads to deeper remissions with no detectable cancer cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Atlanta Cancer Center

    RECRUITING

    Newnan, Georgia, 30265, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Irvine Lennar

    RECRUITING

    Irvine, California, 92618, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope at Long Beach Elm

    RECRUITING

    Long Beach, California, 90813, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    NOT_YET_RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • Medical College of Wisconsin

    NOT_YET_RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Email: •••••@•••••

    Contact

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.