New depression drug tested for Long-Term safety and effectiveness

NCT ID NCT06922110

ENROLLING_BY_INVITATION Disease control Sponsor: Xenon Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the long-term safety and effectiveness of azetukalner in adults with major depressive disorder. Participants must have successfully completed a previous phase 3 study of this drug. The goal is to monitor side effects and track changes in depression symptoms over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

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Locations

Accel Research Sites - Lakeland

Lakeland, Florida, 33803, United States
Accel Research Sites - St. Petersburg-Largo

Largo, Florida, 33777, United States
Adams Clinical - Boston

Boston, Massachusetts, 02116, United States
Adams Clinical - Watertown

Watertown, Massachusetts, 02472, United States
Advanced Discovery Research, Llc

Atlanta, Georgia, 30318, United States
Advanced Quality Medical Research, LLC

Orland Park, Illinois, 60462, United States
Artemis Institute For Clinical Research - San Diego

San Diego, California, 92123, United States
Atp Clinical Research

Orange, California, 92866, United States
Austin Clinical Trial Partners

Austin, Texas, 78737, United States
Bio Behavioral Health

Toms River, New Jersey, 08755, United States
Bioscience Research Llc.

Mount Kisco, New York, 10549, United States
Boeson Research Pvu

Provo, Utah, 84604, United States
Boston Clinical Trials Llc

Boston, Massachusetts, 02131, United States
Calneuro Research Group, Inc.

Los Angeles, California, 90025, United States
Cenexel Cit - Bellflower

Bellflower, California, 90706, United States
Cenexel Cnr - Sherman Oaks

Sherman Oaks, California, 91403-2131, United States
Cenexel Cns - Torrance

Torrance, California, 90501, United States
Cenexel Iresearch - Atlanta

Decatur, Georgia, 30030, United States
Cenexel Iresearch - Savannah

Savannah, Georgia, 31405, United States
Center For Emotional Fitness

Cherry Hill, New Jersey, 08002, United States
Clinical Neuroscience Solutions Inc. - Jacksonville

Jacksonville, Florida, 32256, United States
Clinical Neuroscience Solutions Inc. - Orlando

Orlando, Florida, 32801, United States
Clinical Neuroscience Solutions, Inc.

Memphis, Tennessee, 38119, United States
Cns Clinical Research - Coral Springs

Coral Springs, Florida, 33067, United States
Combined Research Orlando Phase I-Iv

Orlando, Florida, 32807, United States
Core Clinical Research

Everett, Washington, 98201, United States
DelRicht Research

Atlanta, Georgia, 30329, United States
Delricht Research - Plano

Plano, Texas, 75024, United States
Elixia MA, LLC

Springfield, Massachusetts, 01103, United States
Equipath Health and Research Tampa Bay, Llc

Riverview, Florida, 33578, United States
Excell Research Inc.

Oceanside, California, 92056, United States
Fieve Clinical Research (Fcr), Inc.

New York, New York, 10017-1921, United States
Grayline Research Center

Wichita Falls, Texas, 76309, United States
Gulfcoast Clinical Research Center

Fort Myers, Florida, 33912, United States
Harmony Clinical Research Inc

North Miami Beach, Florida, 33162, United States
IMA Clinical Research

Chicago, Illinois, 60634, United States
Ima Clinical Research - Las Vegas

Las Vegas, Nevada, 89102, United States
Ima Clinical Research - Nyc Uptown

New York, New York, 10128, United States
Ima Clinical Research - Phoenix

Phoenix, Arizona, 85012, United States
Insight Clinical Trials Llc

Independence, Ohio, 44131, United States
Institute of Living - Clinical Trials Unit

Hartford, Connecticut, 06106, United States
Integrative Clinical Trials, Llc

Brooklyn, New York, 11229, United States
Lehigh Center For Clinical Research

Allentown, Pennsylvania, 18103, United States
Neoclinical Research

Hialeah, Florida, 33016, United States
New Hope Clinical Research

Charlotte, North Carolina, 28211, United States
Nrc Research Institute

Orange, California, 92868, United States
Pacific Clinical Research Management

Upland, California, 91786, United States
Pahl Pharmaceutical Professionals Llc

Oklahoma City, Oklahoma, 73112, United States
Panhandle Research and Medical Clinic

Pensacola, Florida, 32502, United States
Pharmasouth Research

Coral Gables, Florida, 33146, United States
Psych Atlanta, Pc

Marietta, Georgia, 30060, United States
Psychiatric Care and Research Center

O'Fallon, Missouri, 63368, United States
Redbird Research

Las Vegas, Nevada, 89119, United States
Richmond Behavioral Associates

Staten Island, New York, 10314, United States
Sanro Clinical Research Group, Llc

Bryant, Arkansas, 72022, United States
Sarkis Clinical Trials

Gainesville, Florida, 32607, United States
Sooner Clinical Research

Oklahoma City, Oklahoma, 73116, United States
St. Charles Psychiatric Associates - Midwest Research Group

Saint Charles, Missouri, 63304, United States
Sunwise Clinical Research

Walnut Creek, California, 94596, United States
Synexus - Atlanta

Atlanta, Georgia, 30328, United States
Vitalix Clinical - Worcester

Worcester, Massachusetts, 01608, United States
Woodland International Research Group

Little Rock, Arkansas, 72211, United States
Woodland Research Northwest

Rogers, Arkansas, 72758, United States