Xenon Pharmaceuticals Inc.

This study tests an experimental drug called XEN1101 for adults with focal-onset seizures (a type of epilepsy). About 360 participants will receive either the drug or a placebo, added to their current seizure medications. The goal is to see if XEN1101 safely reduces seizure frequ…

This study tests an experimental drug called XEN1101 for people aged 12 and older with primary generalized tonic-clonic seizures (a type of severe seizure). Participants will take the drug or a placebo alongside their current seizure medications. The goal is to see if XEN1101 saf…

This study tests an experimental drug called azetukalner to see if it can safely reduce depression in people with bipolar I or II disorder. About 400 adults currently in a depressive episode will receive either the drug or a placebo for 6 weeks. The main goal is to measure change…

This study tests an experimental drug called azetukalner in 450 adults with moderate-to-severe major depression. Participants take the drug or a placebo daily for 6 weeks to see if it reduces depression symptoms like low mood and loss of interest. The goal is to find a new treatm…

This study tests a new drug called azetukalner for adults with moderate-to-severe major depression. About 450 people will receive either the drug or a placebo for 6 weeks. The goal is to see if the drug reduces depression symptoms and improves pleasure in daily life.