New pill could lift bipolar depression in just weeks

NCT ID NCT07172516

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 24 times

Summary

This study tests a new drug called azetukalner for people with bipolar I or II disorder who are currently in a depressive episode. About 400 adults will receive either the drug or a placebo to see if it safely improves mood and pleasure. The main goal is to measure changes in depression scores after 6 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ATP Clinical Research

    RECRUITING

    Orange, California, 92866, United States

  • Atlanta Center for Medical Research

    RECRUITING

    Atlanta, Georgia, 30331, United States

  • CenExel iResearch

    RECRUITING

    Decatur, Georgia, 30030, United States

  • Central Miami Medical Institute

    RECRUITING

    Miami, Florida, 33125, United States

  • Clinical Innovations Inc

    RECRUITING

    Bellflower, California, 90706, United States

  • Clinical Innovations Inc

    RECRUITING

    Riverside, California, 92506, United States

  • Clinical Neuroscience Solutions, Inc

    RECRUITING

    Orlando, Florida, 32801, United States

  • Clinical Neuroscience Solutions, Inc

    RECRUITING

    Memphis, Tennessee, 38119, United States

  • Clinical Neuroscience Solutions, Inc.

    RECRUITING

    Jacksonville, Florida, 32256, United States

  • DelRicht Research

    RECRUITING

    Charlotte, North Carolina, 28210, United States

  • Denali Health Atlanta, LLC

    RECRUITING

    Stone Mountain, Georgia, 30083, United States

  • Eastside Therapeutics Resources, INC dba Core Clinical Research

    RECRUITING

    Everett, Washington, 98201, United States

  • Elevate Synapsis, LLC

    RECRUITING

    Atascocita, Texas, 77346, United States

  • Grayline Research Center

    RECRUITING

    Wichita Falls, Texas, 76309, United States

  • Integrative Clinical Trials LLC

    RECRUITING

    Brooklyn, New York, 11229, United States

  • Lehigh Center for Clinical Research

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

  • Lumina Clinical Research Center

    RECRUITING

    Cherry Hill, New Jersey, 08002, United States

  • NRC Research Institute

    RECRUITING

    Orange, California, 92868, United States

  • Neurobehavioral Research Inc

    RECRUITING

    Cedarhurst, New York, 11516, United States

  • Noble Clinical Research

    RECRUITING

    Tucson, Arizona, 85704, United States

  • PharmaSouth Research, LLC

    RECRUITING

    Coral Gables, Florida, 33146, United States

  • ProScience Research Group

    RECRUITING

    Culver City, California, 90230, United States

  • Psychiatric Care and Research Center

    RECRUITING

    O'Fallon, Missouri, 63368, United States

  • Redbird Clinical Research, LLC

    RECRUITING

    Las Vegas, Nevada, 89119, United States

  • Synexus Clinical Research, Inc.

    RECRUITING

    Atlanta, Georgia, 30328, United States

  • Woodland International Research Group

    RECRUITING

    Little Rock, Arkansas, 72211, United States

  • Woodland Research Northwest

    RECRUITING

    Rogers, Arkansas, 72758, United States

Conditions

Explore the condition pages connected to this study.