New pill shows promise for Long-Term IBD control

NCT ID NCT06764615

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests the long-term safety of an oral drug called zasocitinib (TAK-279) in adults with moderate to severe Crohn's disease or ulcerative colitis. Participants who responded to the drug in earlier studies can continue treatment for up to 3 years. The main goal is to see if the drug remains safe and helps control bowel inflammation over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

zasocitinib (TAK-279)

What this could lead to

If successful, this could show that zasocitinib is safe and effective for long-term control of inflammatory bowel disease symptoms.

What could go wrong

This is an early-phase extension study with no placebo group, so results may not confirm long-term benefits. Side effects or lack of sustained response are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centrum Medyczne MedykSp. z o.o. Sp. K.

    RECRUITING

    Lublin, 35-326, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chongqing General Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 400013, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Endomed

    RECRUITING

    Košice, 4013, Slovakia

    Contact

    Contact Email: •••••@•••••

  • Gastromed Kopon Zmudzinski i Wspolnicy Sp.j.Specjalistyczne Centrum Gastrologii i Endoskopii Specj

    RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hepato-Gastroenterologie HK s.r.o.

    RECRUITING

    Hradec Králové, 500 12, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Inje University Haeundae Paik Hospital

    RECRUITING

    Haeundae, Busan Gwangyeogsi, 48108, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Pannonia Maganorvosi Centrum

    RECRUITING

    Budapest, 1136, Hungary

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Renji Hospital Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 2000127, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Antonius Ziekenhuis

    RECRUITING

    Tilburg, North Brabant, 5022GC, Netherlands

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangdong, Guangdong, 510080, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510655, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Twoja Przychodnia - Szczecinskie Centrum Medyczne

    RECRUITING

    Szczecin, 71-434, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tyler Research Institute, LLC

    RECRUITING

    Tyler, Texas, 75701, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • WIP Warsaw IBD Point Profesor Kierkus

    RECRUITING

    Warsaw, 04-730, Poland

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Woodholme Gastroenterology Associates

    RECRUITING

    Glen Burnie, Maryland, 21061, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yonsei University Wonju Severance Christian Hospital

    RECRUITING

    Wŏnju, Gangwon-do, 220-701, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••