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New pill shows promise for Long-Term IBD control

NCT ID NCT06764615

Recruiting now Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests the long-term safety of an oral drug called zasocitinib (TAK-279) in adults with moderate to severe Crohn's disease or ulcerative colitis. Participants who responded to the drug in earlier studies can continue treatment for up to 3 years. The main goal is to see if the drug remains safe and helps control bowel inflammation over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
zasocitinib (TAK-279)
What this could lead to
If successful, this could show that zasocitinib is safe and effective for long-term control of inflammatory bowel disease symptoms.
What could go wrong
This is an early-phase extension study with no placebo group, so results may not confirm long-term benefits. Side effects or lack of sustained response are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Crohn disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN'S DISEASE ULCERATIVE COLITIS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Centrum Medyczne MedykSp. z o.o. Sp. K.

    RECRUITING

    Lublin, 35-326, Poland

  • Chongqing General Hospital

    RECRUITING

    Chongqing, Chongqing Municipality, 400013, China

  • Endomed

    RECRUITING

    Košice, 4013, Slovakia

  • Gastromed Kopon Zmudzinski i Wspolnicy Sp.j.Specjalistyczne Centrum Gastrologii i Endoskopii Specj

    RECRUITING

    Torun, Kuyavian-Pomeranian Voivodeship, 87-100, Poland

  • Hepato-Gastroenterologie HK s.r.o.

    RECRUITING

    Hradec Králové, 500 12, Czechia

  • Inje University Haeundae Paik Hospital

    RECRUITING

    Haeundae, Busan Gwangyeogsi, 48108, South Korea

  • Pannonia Maganorvosi Centrum

    RECRUITING

    Budapest, 1136, Hungary

  • Renji Hospital Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 2000127, China

  • St. Antonius Ziekenhuis

    RECRUITING

    Tilburg, North Brabant, 5022GC, Netherlands

  • The First Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangdong, Guangdong, 510080, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 510655, China

  • Twoja Przychodnia - Szczecinskie Centrum Medyczne

    RECRUITING

    Szczecin, 71-434, Poland

  • Tyler Research Institute, LLC

    RECRUITING

    Tyler, Texas, 75701, United States

  • WIP Warsaw IBD Point Profesor Kierkus

    RECRUITING

    Warsaw, 04-730, Poland

  • Woodholme Gastroenterology Associates

    RECRUITING

    Glen Burnie, Maryland, 21061, United States

  • Yonsei University Wonju Severance Christian Hospital

    RECRUITING

    Wŏnju, Gangwon-do, 220-701, South Korea

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