ALS drug safety check: new study tests Long-Term effects

NCT ID NCT07571200

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at the long-term safety of an experimental drug called LY4256984 for people with ALS. It enrolls up to 32 participants who have completed a prior ALS trial. The study will follow them for at least 96 weeks to see how well the drug is tolerated over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

LY4256984

What this could lead to

If successful, this could help confirm that these experimental drugs are safe enough to use in larger trials for ALS.

What could go wrong

This is a very early (Phase 1) study with only 32 people. It focuses on safety, not effectiveness, so it may not lead to a treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Universitari de Bellvitge

    NOT_YET_RECRUITING

    L'Hospitalet de Llobregat, 08907, Spain

    Contact

  • Hospital Universitari i Politecnic La Fe

    NOT_YET_RECRUITING

    Valencia, 46026, Spain

    Contact

  • McGill University Health Centre

    RECRUITING

    Montreal, H4A 3J1, Canada

    Contact Phone: •••-•••-••••

    Contact

  • Sunnybrook Research Institute

    NOT_YET_RECRUITING

    Toronto, M4N 3M5, Canada

    Contact

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, 3000, Belgium

    Contact Phone: •••-•••-••••

    Contact

  • Universitaetsklinikum Ulm

    NOT_YET_RECRUITING

    Ulm, 89081, Germany

    Contact Phone: •••-•••-••••

    Contact

  • Universitair Medisch Centrum Utrecht

    NOT_YET_RECRUITING

    Utrecht, 3584 CX, Netherlands

    Contact Phone: •••-•••-••••

    Contact

  • Universitätsklinikum Schleswig-Holstein

    NOT_YET_RECRUITING

    Lübeck, 23538, Germany

    Contact Phone: •••-•••-••••

    Contact

  • Universitätsmedizin Rostock

    NOT_YET_RECRUITING

    Rostock, 18147, Germany

    Contact Phone: •••-•••-••••

    Contact