Do anal fistulas stay away long-term after combo therapy in Crohn's? new study investigates.

NCT ID NCT06514092

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 63 Crohn's disease patients who had an anal fistula treated with anti-TNF drugs and a seton drain. Researchers tracked how long the fistula stayed closed and what factors might cause it to come back. The goal is to better understand long-term outcomes and improve treatment plans for people with this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anti-TNF therapy (a type of biologic drug) and seton drainage (a surgical thread placed in the fistula to keep it open and allow drainage)

What this could lead to

If successful, this research could help doctors better predict which Crohn's patients are at higher risk of fistula recurrence and tailor follow-up care accordingly.

What could go wrong

This is a small, completed observational study (63 patients) from a single hospital, so results may not apply to all patients. It does not test a new treatment, only looks back at past outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Toulouse

    Toulouse, France