Do anal fistulas stay away long-term after combo therapy in Crohn's? new study investigates.

NCT ID NCT06514092

Completed Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at 63 Crohn's disease patients who had an anal fistula treated with anti-TNF drugs and a seton drain. Researchers tracked how long the fistula stayed closed and what factors might cause it to come back. The goal is to better understand long-term outcomes and improve treatment plans for people with this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: anti-TNF therapy (a type of biologic drug) and seton drainage (a surgical thread placed in the fistula to keep it open and allow drainage)
What this could lead to: If successful, this research could help doctors better predict which Crohn's patients are at higher risk of fistula recurrence and tailor follow-up care accordingly.
What could go wrong: This is a small, completed observational study (63 patients) from a single hospital, so results may not apply to all patients. It does not test a new treatment, only looks back at past outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CROHN DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CROHN DISEASE

Contacts and locations

Locations

CHU de Toulouse

Toulouse, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.