Could breathing different gases clear long COVID brain fog?
NCT ID NCT06614309
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Mayo Clinic pilot study tests whether breathing controlled levels of oxygen or carbon dioxide can help people with Long COVID brain fog. 45 participants will try short sessions of these gas mixtures and report changes in brain fog, fatigue, and blood flow. The goal is to see if this non-invasive approach is worth studying further.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
breathing controlled levels of oxygen and carbon dioxide
What this could lead to
If it works, this could point toward a simple, non-invasive way to reduce brain fog and fatigue in people with Long COVID.
What could go wrong
This is a very early pilot study with only 45 people. The treatment is experimental and may not improve symptoms. Some people may feel discomfort from the gas mixtures.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic in Arizona
RECRUITINGScottsdale, Arizona, 85259, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••