New combo therapy aims to deepen remission in CLL

NCT ID NCT05971251

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 24 times

Summary

This early-phase study tests adding a targeted drug, loncastuximab tesirine, to the standard treatment acalabrutinib for people with chronic lymphocytic leukemia (CLL). The main goal is to find the safest dose of the combination. Researchers will also check if the combo can make cancer undetectable in the blood at 6 and 12 months. About 24 adults with CLL will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

Conditions

Explore the condition pages connected to this study.