Major study on rare childhood liver diseases halted

NCT ID NCT00571272

Terminated Knowledge-focused Sponsor: Arbor Research Collaborative for Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed children and young adults with genetic liver diseases that cause bile buildup. The goal was to track how these diseases progress over time, including the need for liver transplants or other complications. No treatments were tested; the aim was simply to learn more about these rare conditions.

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Conditions

The condition(s) this trial relates to.

Alagille syndrome alpha 1-antitrypsin deficiency benign recurrent intrahepatic cholestasis cholestasis Cholestasis, progressive familial intrahepatic 1 hereditary disease inborn disorder of bile acid synthesis liver disorder progressive familial intrahepatic cholestasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALAGILLE SYNDROME ALPHA 1-ANTITRYPSIN DEFICIENCY LIVER DISEASES

Contacts and locations

Locations

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States
Baylor School of Medicine

Houston, Texas, 77030, United States
Children's Healthcare of Atlanta - Emory University

Atlanta, Georgia, 30322, United States
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Children's Hospital of Los Angeles

Los Angeles, California, 90027, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Cincinnati's Children's Memorial Hospital

Cincinnati, Ohio, 60190, United States
Johns Hopkins University Hospital

Baltimore, Maryland, 21287, United States
Mount Sinai School of Medicine

New York, New York, 10029, United States
Riley Hospital for Children

Indianapolis, Indiana, 46202, United States
Seattle Children's Hospital

Seattle, Washington, 98105, United States
St. Louis University - Cardinal Glennon Children's Medical Center

St Louis, Missouri, 63104, United States
The Hospital for Sick Children

Toronto, Ontario, M5G 1X8, Canada
UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, 15224, United States
University of California at San Francisco (UCSF)

San Francisco, California, 94143, United States
University of Utah

Salt Lake City, Utah, 84113, United States
Washington University School of Medicine/St. Louis Children's Hospital

St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.