Major study on rare childhood liver diseases halted midway

NCT ID NCT00571272

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 30 times

Summary

This study followed children and young adults with genetic liver diseases that cause bile buildup (cholestasis), including Alagille syndrome and alpha-1 antitrypsin deficiency. Researchers tracked disease progression, such as need for liver transplant or growth problems, to better understand these conditions. The study did not test any new treatments and is currently suspended.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    Chicago, Illinois, 60611, United States

  • Baylor School of Medicine

    Houston, Texas, 77030, United States

  • Children's Healthcare of Atlanta - Emory University

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Los Angeles

    Los Angeles, California, 90027, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati's Children's Memorial Hospital

    Cincinnati, Ohio, 60190, United States

  • Johns Hopkins University Hospital

    Baltimore, Maryland, 21287, United States

  • Mount Sinai School of Medicine

    New York, New York, 10029, United States

  • Riley Hospital for Children

    Indianapolis, Indiana, 46202, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • St. Louis University - Cardinal Glennon Children's Medical Center

    St Louis, Missouri, 63104, United States

  • The Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • UPMC Children's Hospital of Pittsburgh

    Pittsburgh, Pennsylvania, 15224, United States

  • University of California at San Francisco (UCSF)

    San Francisco, California, 94143, United States

  • University of Utah

    Salt Lake City, Utah, 84113, United States

  • Washington University School of Medicine/St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.