Gut bacteria boost may help immunotherapy fight advanced melanoma
NCT ID NCT06623461
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 34 times
Summary
This study tests whether adding a fecal microbiota transplant called LND101 to standard immunotherapy can help keep advanced melanoma from growing or spreading. About 128 people with stage IV or unresectable melanoma will receive either immunotherapy alone or with LND101. The goal is to see if changing gut bacteria improves how well the cancer responds to treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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BCCA - Abbotsford
RECRUITINGAbbotsford British Columbia, British Columbia, V2S 0C2, Canada
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BCCA - Surrey
RECRUITINGSurrey, British Columbia, V3V 1Z2, Canada
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BCCA - Vancouver
RECRUITINGVancouver, British Columbia, V5Z 4E6, Canada
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CHUM-Centre Hospitalier de l'Universite de Montreal
RECRUITINGMontreal, Quebec, H2X 3E4, Canada
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Centre Integre de Sante et de Services Sociaux
RECRUITINGGreenfield Park, Quebec, J4V 2H1, Canada
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Centre hospitalier regional de Trois-Rivieres
RECRUITINGTrois-Rivières, Quebec, G8Z 3R9, Canada
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Hotel-Dieu de Quebec
RECRUITINGQuébec, Quebec, G1R 2J6, Canada
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Juravinski Cancer Centre at Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8V 5C2, Canada
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London Health Sciences Centre Research Inc.
RECRUITINGLondon, Ontario, N6A 5W9, Canada
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Odette Cancer Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
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Ottawa Hospital Research Institute
RECRUITINGOttawa, Ontario, K1H 8L6, Canada
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Stronach Regional Health Centre at Southlake
RECRUITINGNewmarket, Ontario, L3Y 2P9, Canada
Contact Phone: •••-•••-••••
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The Jewish General Hospital
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
Contact Phone: •••-•••-••••
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University Health Network
RECRUITINGToronto, Ontario, M5G 2M9, Canada
Contact Phone: •••-•••-••••
Conditions
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