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Could a gut bacteria boost melanoma treatment? new trial aims to find out

NCT ID NCT06623461

Recruiting now Disease control Sponsor: Canadian Cancer Trials Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a fecal microbiota transplant called LND101 to standard immunotherapy can help stop advanced melanoma from growing or spreading. About 128 people with stage IV or unresectable melanoma will receive either immunotherapy alone or immunotherapy plus LND101. The goal is to see if changing gut bacteria improves how well the cancer is controlled.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA

Contacts and locations

Locations

  • BCCA - Abbotsford

    RECRUITING

    Abbotsford British Columbia, British Columbia, V2S 0C2, Canada

  • BCCA - Surrey

    RECRUITING

    Surrey, British Columbia, V3V 1Z2, Canada

  • BCCA - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

  • CHUM-Centre Hospitalier de l'Universite de Montreal

    RECRUITING

    Montreal, Quebec, H2X 3E4, Canada

  • Centre Integre de Sante et de Services Sociaux

    RECRUITING

    Greenfield Park, Quebec, J4V 2H1, Canada

  • Centre hospitalier regional de Trois-Rivieres

    RECRUITING

    Trois-Rivières, Quebec, G8Z 3R9, Canada

  • Hotel-Dieu de Quebec

    RECRUITING

    Québec, Quebec, G1R 2J6, Canada

  • Juravinski Cancer Centre at Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

  • London Health Sciences Centre Research Inc.

    RECRUITING

    London, Ontario, N6A 5W9, Canada

  • Odette Cancer Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

  • Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

  • Stronach Regional Health Centre at Southlake

    RECRUITING

    Newmarket, Ontario, L3Y 2P9, Canada

  • The Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

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