Iodine trick may help surgeons remove all precancerous cervical cells
NCT ID NCT05132114
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether applying Lugol's iodine during LLETZ surgery helps doctors remove all precancerous cervical tissue. Iodine stains healthy tissue brown, making abnormal areas easier to see. The trial involved 230 women with cervical dysplasia and compared standard surgery to surgery with iodine staining. The goal was to see if iodine reduces the rate of incomplete removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lugol's iodine solution
What this could lead to
If successful, this technique could lower the chance that precancerous cells are left behind after surgery, reducing the need for repeat procedures.
What could go wrong
This is a completed early-stage study with 230 participants. The benefit may be small or not apply to all women, and iodine allergy is a rare but possible risk.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Marien Hospital Herne
Herne, North Rhine-Westphalia, 44625, Germany