Could a vaginal gel replace surgery for cervical dysplasia?
NCT ID NCT07429071
First seen Jun 25, 2026 · Last updated Aug 04, 2026 · Updated 4 times
Summary
This early-stage trial tests whether a mushroom-based vaginal gel (Papilocare) can help clear HPV and reverse mild to moderate cervical dysplasia (CIN1/CIN2). Seventy women aged 30-50 will either use the gel for 6 months or follow the standard 'watch and wait' approach. The study aims to see if the gel leads to better outcomes without invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Papilocare vaginal gel (Coriolus versicolor-based)
- What this could lead to
- If it works, this could offer a non-invasive treatment option for early cervical dysplasia and help clear HPV, reducing the need for surgery.
- What could go wrong
- This is a very early, small trial (70 women) with no results yet. The gel may not work better than watchful waiting, and long-term effects are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Gynaecology and Obstetrics
RECRUITINGHorsens, 8700, Denmark
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Department of Gynaecology and Obstetrics
RECRUITINGRanders, Denmark
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