Tai-Chi and lactulose combo tested to stop falls in liver patients

NCT ID NCT05794555

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed Phase 3 trial tested whether a combination of lactulose (a medicine) and virtual Tai-Chi (a gentle exercise) could reduce falls and other serious events in 230 people with cirrhosis and portal hypertension. Participants were randomly assigned to different sequences of these interventions over 24 weeks. The study aimed to see if this approach could lower the risk of falls, confusion (hepatic encephalopathy), and need for liver transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lactulose and virtual Tai-Chi

What this could lead to

If successful, this could offer a practical, non-drug way to reduce falls and serious liver complications in people with cirrhosis.

What could go wrong

This is a completed Phase 3 trial, but results are not yet published. The combination may not prove better than usual care, and individual results may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver portal hypertension flatfoot prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Scott & White Research Institute (BSW)

    Dallas, Texas, 75246, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States