Tai-Chi and lactulose combo tested to stop falls in liver patients

NCT ID NCT05794555

Completed Prevention Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 31, 2026 · Updated 2 times

Summary

This completed Phase 3 trial tested whether a combination of lactulose (a medicine) and virtual Tai-Chi (a gentle exercise) could reduce falls and other serious events in 230 people with cirrhosis and portal hypertension. Participants were randomly assigned to different sequences of these interventions over 24 weeks. The study aimed to see if this approach could lower the risk of falls, confusion (hepatic encephalopathy), and need for liver transplant.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lactulose and virtual Tai-Chi
What this could lead to: If successful, this could offer a practical, non-drug way to reduce falls and serious liver complications in people with cirrhosis.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. The combination may not prove better than usual care, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver portal hypertension flatfoot prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CIRRHOSIS, LIVER PORTAL HYPERTENSION

Contacts and locations

Locations

Baylor Scott & White Research Institute (BSW)

Dallas, Texas, 75246, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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