Mini livers in a dish reveal how a common gene variant fuels fatty liver disease
NCT ID NCT06856252
First seen Nov 20, 2025 · Last updated May 16, 2026 · Updated 20 times
Summary
This study uses tiny, lab-grown liver models called organoids to understand how a specific gene change (PNPLA3 I148M) contributes to non-alcoholic steatohepatitis (NASH), a serious form of fatty liver disease. Researchers will create these models from liver cells donated by 60 adults undergoing liver procedures. The goal is to uncover disease mechanisms and find new biomarkers, not to test a treatment.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NAFLD are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Istituto di Ricovero e Cura a Carattere Scientifico di natura pubblica
RECRUITINGMilan, Milano, 20122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.