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Lipedema may have a distinct fat distribution signature

NCT ID NCT07878299

NEW Knowledge-focused Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 16, 2026 · Last updated Oct 16, 2026

Summary

Researchers compare body composition in women with lipedema and women with obesity who have similar age and body mass index. They use bioelectrical impedance analysis to measure fat and muscle in the legs, arms, and trunk. The study tests whether women with lipedema have a higher proportion of their total body fat in their legs. It also looks at how these measurements relate to pain and leg function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study finds a distinct fat distribution pattern in lipedema, it could help doctors tell lipedema apart from obesity more easily and guide better care.
What could go wrong
This is an observational study with 200 participants, so it can only show associations, not cause and effect. The findings may not apply to all women with lipedema or obesity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of adult female patients diagnosed with lipedema who present to the Physical Medicine and Rehabilitation Outpatient Clinic during the study period, along with female volunteers with a similar mean BMI who are evaluated at the outpatient clinic.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1\. Inclusion Criteria (Lipedema Group) 1. Being female. 2. Being between 18-65 years of age. 3. Having received a diagnosis of lipedema based on clinical evaluation. 4. Being willing to participate in the study and signing the written informed consent form. 2\. Inclusion Criteria (BMI-Matched Obese Group) 1. Being female. 2. Being between 18-65 years of age. 3. Not meeting the diagnostic criteria for lipedema on clinical evaluation. 4. Showing similar characteristics to the lipedema group in terms of age and BMI. 5. Being willing to participate in the study and signing the written informed consent form. Exclusion Criteria: 1. Being pregnant or breastfeeding. 2. Having a diagnosis of primary or secondary lymphedema. 3. Having clinically advanced-stage chronic venous insufficiency, an active venous ulcer, or a history of acute deep vein thrombosis. 4. Having a history of surgery or serious trauma within the last 6 months. 5. Having an active infection, cellulitis, or open wound. 6. Presence of edema due to congestive heart failure, advanced renal failure, or decompensated liver disease. 7. Having a diagnosis of active malignancy. 8. Having a neurological, rheumatological, or serious musculoskeletal disease that could affect the assessment. 9. Being unable to comply with study procedures or not providing informed consent.

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Conditions

The condition(s) this trial relates to.

erythema multiforme Lipedema Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bioelectrical impedance analysis Body mass index Lipedema Obesity

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Department of Physical Medicine and Rehabilitation, Health Sciences University Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Uskudar

    RECRUITING

    Istanbul, Uskudar, Turkey (Türkiye)

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