LIPEDEMA

This study uses special ultrasound techniques to find clear differences between lymphedema and lipedema, two chronic conditions that cause leg swelling and are often hard to tell apart. Researchers will compare 75 adults—those with lymphedema, those with lipedema, and healthy vol…

This study tests two non-invasive treatments—ultrasound fat cavitation and pneumatic compression—to see which better reduces fat thickness in women with mild to moderate lipedema. Lipedema is a painful fat disorder affecting millions of women. The goal is to find a safe, surgery-…

This study investigates how lipedema — a condition causing abnormal fat buildup in the legs — affects muscle structure and walking. Researchers will use ultrasound to measure leg muscle and tendon thickness in 45 women with lipedema and compare them to 45 healthy women. A foot-pr…

Lipedema is a chronic condition causing painful fat buildup in the legs, mostly in women. This study is testing whether a Turkish translation of the Rapprich Lipedema Symptomatic Assessment Questionnaire is a reliable and valid tool for measuring symptom severity. Researchers wil…

This study looks at whether vein problems are linked to pain, swelling, and daily function in women with lipedema. Researchers will use ultrasound to check leg veins and ask participants about their symptoms. The goal is to better understand how these conditions interact, which c…

This study will compare women with knee osteoarthritis who also have lipedema (a fat tissue disorder) to those without lipedema. Researchers will use ultrasound to measure knee cartilage thickness and questionnaires to assess pain and daily function. The goal is to understand if …

This study looks at how metabolic markers like insulin resistance and body measurements relate to pain and central sensitization in women with lipedema. Researchers will assess 59 women using questionnaires and physical measurements. The goal is to better understand these connect…

This study looks at whether women with lipedema have flatter feet and looser joints compared to women without the condition. Researchers will use foot X-rays and flexibility tests to measure these differences. The goal is to better understand how lipedema affects foot function an…

This study is creating a collection of blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. Researchers will use these samples to study inflammation, blood clotting, and other biological pathways. The goal is to build a resource tha…

This study examines whether women with lipedema have a condition called central sensitization, where the nervous system becomes overly sensitive to pain. Researchers will measure pain thresholds and use ultrasound in 50 participants, comparing them to healthy volunteers. The goal…