LIPEDEMA

This study is testing whether advanced, non-invasive ultrasound techniques can help doctors accurately tell the difference between two conditions that cause leg swelling: lymphedema and lipedema. Researchers will compare ultrasound scans from 75 people—some with lymphedema, some …

This study aims to see if two non-surgical treatments can reduce painful fat buildup in women with lipedema. Researchers will compare ultrasound fat cavitation and pneumatic compression therapy, both added to standard care, against standard care alone. The goal is to find better …

This study aims to understand how a person's metabolic health—including markers like insulin resistance and cholesterol—might be connected to pain and a heightened pain response (central sensitization) in women with lipedema. Researchers will observe and measure these factors in …

This study aims to create a long-term collection of biological samples to help researchers better understand heart and blood vessel diseases. It will collect blood, urine, and stool samples from 500 adults who have or are at risk for these conditions. The goal is to build a share…

This study aims to understand how lipedema affects exercise habits and physical activity. Researchers will compare 100 women with lipedema to healthy women, asking about their exercise routines, barriers they face, and experiences during and after activity. The goal is to identif…

This study aims to understand if a condition called 'central sensitization'—where the nervous system becomes overly sensitive to pain—is present in people with lipedema. Researchers will compare pain sensitivity, ultrasound scans, and quality of life in 50 women with lipedema aga…

This study aims to understand if women with lipedema, a chronic fat tissue disorder, are more likely to have flexible joints and flat feet compared to similar women without the condition. Researchers will compare foot X-rays and ask questions about pain and function in 32 partici…