Could a simple vibration machine help blood cancer patients?

NCT ID NCT05893940

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether low-intensity mechanical stimulation (LIMS) vibration therapy can help blood cancer patients who are about to receive a stem cell transplant or cell therapy. The vibration board sends gentle waves through the bones, which may stimulate bone growth, improve muscle strength, and boost immune T-cell activity. Researchers will measure how much time patients can use the device and whether it improves bone density and the effectiveness of CAR T-cell therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Low Intensity Vibration Therapy (LIMS)
What this could lead to
If it works, this could offer a simple, drug-free way to prevent bone loss and boost immune cell activity in blood cancer patients undergoing transplant or cell therapy.
What could go wrong
This is an early-stage trial with only 75 participants, so results may not apply to everyone. The vibration therapy may not provide meaningful benefit, and its effect on T-cell activation is still uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roswell Park Comprehensive Cancer Center

    RECRUITING

    Buffalo, New York, 14263, United States

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