Can a mediterranean diet and exercise beat metabolic syndrome?

NCT ID NCT06857929

Recruiting now Disease control Sponsor: IMDEA Food Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a reduced-calorie Mediterranean diet plus regular exercise helps middle-aged adults (30-50 years) with metabolic syndrome lose weight and keep it off. About 106 participants will either follow this lifestyle program or receive standard care. Researchers will measure weight loss and changes in waist size and blood fats over 6 to 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: energy-reduced Mediterranean diet plus physical activity program
What this could lead to: If successful, this could show that a structured diet and exercise program helps middle-aged adults lose weight and improve heart health markers.
What could go wrong: This is a small early-stage trial with no blinding, so results may not apply broadly. Participants may struggle to stick with the lifestyle changes long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Body Weight metabolic syndrome X Motor Activity Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

METABOLIC SYNDROME OBESITY AND OVERWEIGHT OBESITY PREVENTION

Contacts and locations

Locations

IMDEA Nutrition
RECRUITING

Madrid, Madrid, 28049, Spain

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