Numbing ointment could ease pain after hemorrhoid surgery, reduce opioid use
NCT ID NCT07688031
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial tests whether a topical ointment containing two numbing agents (lidocaine and tetracaine) can reduce pain after hemorrhoid surgery. Adults scheduled for elective hemorrhoidectomy will apply the ointment or a placebo every 12 hours for 10 days after surgery. Researchers will measure pain scores, especially after bowel movements, and track how much rescue pain medication participants need. The goal is to see if this ointment offers a safe, effective alternative to opioids for post-surgical pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lidocaine 23% and tetracaine 7% topical ointment
- What this could lead to
- If effective, this ointment could provide a simple, non-opioid way to manage pain after hemorrhoid surgery, reducing the need for stronger painkillers.
- What could go wrong
- This is a small, early-phase trial, so results may not apply to everyone. The ointment may cause skin irritation or allergic reactions, and it might not work better than placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Red UC Christus Hospital
Santiago, RM, Chile
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