New pill could help heart failure patients breathe easier and walk farther

NCT ID NCT05983250

Ongoing Disease control Sponsor: Tenax Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 3 times

Summary

This study tests an oral medication called levosimendan in people who have both pulmonary hypertension (high blood pressure in the lungs) and a type of heart failure where the heart pumps normally but is stiff. The goal is to see if the drug helps them walk farther in 6 minutes compared to a placebo. About 230 adults aged 18 to 85 with moderate to severe symptoms will participate.

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Conditions

The condition(s) this trial relates to.

heart failure pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY HYPERTENSION

Contacts and locations

Locations

Tenax Investigational Site

Tucson, Arizona, 85721, United States
Tenax Investigational Site

La Jolla, California, 92037, United States
Tenax Investigational Site

Los Angeles, California, 90033, United States
Tenax Investigational Site

Los Angeles, California, 90048, United States
Tenax Investigational Site

Sacramento, California, 95817, United States
Tenax Investigational Site

San Francisco, California, 94143, United States
Tenax Investigational Site

Torrance, California, 90502, United States
Tenax Investigational Site

Jacksonville, Florida, 32224, United States
Tenax Investigational Site

Winter Haven, Florida, 33881, United States
Tenax Investigational Site

Atlanta, Georgia, 30322, United States
Tenax Investigational Site

Chicago, Illinois, 60208, United States
Tenax Investigational Site

Chicago, Illinois, 60637, United States
Tenax Investigational Site

Galesburg, Illinois, 61401, United States
Tenax Investigational Site

Indianapolis, Indiana, 46202, United States
Tenax Investigational Site

Indianapolis, Indiana, 46260, United States
Tenax Investigational Site

Louisville, Kentucky, 40202, United States
Tenax Investigational Site

Boston, Massachusetts, 02114, United States
Tenax Investigational Site

Minneapolis, Minnesota, 55455, United States
Tenax Investigational Site

Rochester, Minnesota, 55905, United States
Tenax Investigational Site

St Louis, Missouri, 63136, United States
Tenax Investigational Site

Omaha, Nebraska, 68198, United States
Tenax Investigational Site

New York, New York, 10021, United States
Tenax Investigational Site

New York, New York, 10029, United States
Tenax Investigational Site

Rochester, New York, 14621, United States
Tenax Investigational Site

Roslyn, New York, 11576, United States
Tenax Investigational Site

Durham, North Carolina, 27710, United States
Tenax Investigational Site

Greensboro, North Carolina, 27401, United States
Tenax Investigational Site

Cincinnati, Ohio, 45267, United States
Tenax Investigational Site

Columbus, Ohio, 43214, United States
Tenax Investigational Site

Pittsburgh, Pennsylvania, 15212, United States
Tenax Investigational Site

Providence, Rhode Island, 02903, United States
Tenax Investigational Site

Charleston, South Carolina, 29425, United States
Tenax Investigational Site

Columbia, South Carolina, 29044, United States
Tenax Investigational Site

Dallas, Texas, 75204, United States
Tenax Investigational Site

Dallas, Texas, 75390, United States
Tenax Investigational Site

Lubbock, Texas, 79430, United States
Tenax Investigational Site

Plano, Texas, 75093, United States
Tenax Investigational Site

Murray, Utah, 84107, United States
Tenax Investigational Site

Richmond, Virginia, 23298, United States
Tenax Investigational Site

Madison, Wisconsin, 53792, United States
Tenax Investigational Site

Winnipeg, Manitoba, Canada
Tenax Investigational Site

London, Ontario, N6A 5A5, Canada

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