Heart failure drug levosimendan tested for long-term safety in rare lung-heart condition

NCT ID NCT03624010

First seen Apr 23, 2026 · Last updated May 20, 2026 · Updated 4 times

Summary

This study looked at the safety of using levosimendan over a longer period in 35 people who have both pulmonary hypertension (high blood pressure in the lungs) and a type of heart failure where the heart pumps normally but doesn't fill properly. Participants had already completed a previous study with the drug. The main goal was to track any side effects during extended use.

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Contacts and locations

Locations

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • Stanford Healthcare

    Stanford, California, 94305, United States

  • UPMC Presbyterian Hospital

    Pittsburgh, Pennsylvania, 15213, United States

  • UW Health University Hospital

    Madison, Wisconsin, 53792, United States

  • University of Minnesota Medical Center

    Minneapolis, Minnesota, 55455, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.