Heart failure mystery: scientists probe energy failures in heart and muscles

NCT ID NCT03775577

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why people with a type of heart failure (HFpEF) have trouble exercising. Researchers will measure energy use in the heart and leg muscles using special scans. They aim to link these energy problems to how well patients can walk and exercise. The study does not test any new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could reveal why people with heart failure struggle to exercise, pointing toward future therapies.

What could go wrong

This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••