Could a weekly pill boost sperm count? new trial seeks answers

NCT ID NCT06993155

Recruiting now Disease control Sponsor: ReproNovo Aps Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests three doses of a drug called leflutrozole to see if it can improve semen quality in men with low sperm count and low testosterone. About 200 men aged 18-49 will take either the drug or a placebo once a week for 16 weeks. Researchers will measure changes in sperm count, movement, and shape, and monitor for side effects.

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Conditions

The condition(s) this trial relates to.

hypogonadotropic hypogonadism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOGONADOTROPIC HYPOGONADISM SEMEN QUALITY

Contacts and locations

Locations

ReproNovo Investigational Site
RECRUITING

North Hollywood, California, 91606, United States
ReproNovo Investigational Site
RECRUITING

Pomona, California, 91767, United States
ReproNovo Investigational Site
RECRUITING

Garden City, New York, 11530, United States
ReproNovo Investigational Site
RECRUITING

Middleburg Heights, Ohio, 44130, United States

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