Could a probiotic ease your aching joints?

NCT ID NCT06658821

ENROLLING_BY_INVITATION Symptom relief Sponsor: Chung Shan Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily capsule containing a heat-killed probiotic (LDL557) can improve joint discomfort and inflammation in 100 older adults with early knee or hip arthritis. Participants take either the probiotic or a placebo for a period, and researchers measure changes in pain, stiffness, and daily function using standard arthritis questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: LDL557-HK capsule (heat-killed Lactobacillus delbrueckii subsp. lactis LDL557)
What this could lead to: If it works, this could offer a natural, drug-free option to reduce joint pain and stiffness in early arthritis.
What could go wrong: This is a small, early-stage trial with no blinding details. The supplement may not outperform placebo, and results may not apply to more severe arthritis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Arthralgia arthritic joint disease osteoarthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTHRITIS JOINT PAIN

Contacts and locations

Locations

Chung Shan Medical University

Taichung, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.