Laser hope for scars and scleroderma fizzles in tiny trial

NCT ID NCT04567537

Terminated Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether a special laser could improve scars and skin hardening from scleroderma. Only 6 people took part, and the study was stopped early. Researchers measured scar changes using a standard scale, but the small size and early termination mean we cannot draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: laser treatment
What this could lead to: If successful, this could point toward a non-invasive way to improve the appearance and texture of scars and scleroderma-affected skin.
What could go wrong: The trial was terminated early and included only 6 participants, so results are very limited. It is unclear if the treatment works or is safe for broader use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diffuse scleroderma scleroderma severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCARS SCLERODERMA

Contacts and locations

Locations

MGH Clinical Unit for Research Trials & Outcomes in Skin

Boston, Massachusetts, 02114, United States

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