Could a seizure drug ease chronic pancreatitis pain and reduce opioid side effects?
NCT ID NCT05603702
First seen Mar 18, 2026 · Last updated Apr 29, 2026 · Updated 3 times
Summary
This early-phase study tests whether adding lacosamide, a seizure medication, to standard opioid therapy is safe and tolerable for people with chronic pancreatitis and ongoing abdominal pain. About 24 adults who have been on opioids for at least 4 weeks will take lacosamide for 7 days, and researchers will monitor side effects, compliance, and pain scores. The goal is to see if this combination can reduce pain and the condition called opioid-induced hyperalgesia (increased pain sensitivity from opioids).
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC PAIN are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Mayo Clinic
ACTIVE_NOT_RECRUITINGRochester, Minnesota, 55905, United States
-
Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Stanford University
COMPLETEDStanford, California, 94305, United States
-
University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.