Brain chemistry experiment seeks clues in schizophrenia

NCT ID NCT04013555

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a supplement called N-acetylcysteine (NAC) affects brain chemicals and thinking in 88 adults with schizophrenia or related disorders. Participants took tryptophan to raise a brain chemical called kynurenic acid, then had cognitive tests and brain scans. The goal was to see if NAC could block certain brain changes and improve memory.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Maryland Psychiatric Research Center (MPRC) ; the Treatment Research Program (TRP)

    Catonsville, Maryland, 21228, United States

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