New nerve block could ease knee replacement pain

NCT ID NCT07360392

Recruiting now Symptom relief Sponsor: Amasya University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new nerve block called BiFeS against the standard iPACK block for pain after knee replacement surgery. 88 adults having a knee replacement will be randomly assigned to receive one of the two blocks. The goal is to see which provides better pain relief and helps patients recover faster.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine (local anesthetic)
What this could lead to: If successful, this new nerve block could provide better pain relief and faster recovery after knee replacement surgery.
What could go wrong: This is a small, early-stage trial with only 88 participants, so results may not apply to everyone. The new block might not be better than the standard approach.

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis, knee Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA, REGIONAL ARTHROPLASTY REPLACEMENT, KNEE PAIN, POSTOPERATIVE

Contacts and locations

Locations

Amasya University Sabuncuoğlu Şerefeddin Training and Research Hospital
RECRUITING

Amasya, 05200, Turkey (Türkiye)

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